Here's some very interesting  museums to see:

Pittsburgh Regional History Center
Carnegie Museum of Natural History - new Dinosaur exhibit is here !
Carnegie Science Center - Bodies exhibit is here !
Carnegie Museum of Art
Frick Art & Historical Center
George Westinghouse Virtual Museum - Home of the Most Prolific Inventor on Record.
Andy Warhol Museum
Marvin's Marvelous Mechanical Museum
Pittsburgh Children's Museum
Mattress Factory Art Museum
Air Heritage Museum
Bushy Run Battlefield
Fort Pitt Museum
Frick Car & Carriage Museum
Old Economy Village
Pennsylvania Trolley Museum
Western Pennsylvania Model Railroad Museum
National Aviary
Pittsburgh Zoo and Aquarium
Soldiers & Sailors National Military Museum & Memorial


Phipps Conservatory: Year of Glass 2007
Pittsburgh Zoo & PPG Aquarium : Water's Edge exhibit
Botanic Garden of Western PA: groundbreaking started for new 452 acre aite

more stuff coming soon !!!